By Stefan Silbernagl, Agamemnon Despopoulos jr.
The fifth English variation has been completely revised by way of content material and association of the didactic fabric; just about all of the colour illustrations were drawn anew for better readability. The vast introductory bankruptcy specializes in facets of cytophysiology. as a result of the significantly extended textual content and more suitable illustrative fabric, useful connections are simply famous; new recommendations and present advances in learn are taken absolutely under consideration. major gains are: normal and mobile body structure; Nerve and muscle; Autonomic fearful procedure; Blood; breathing; Acid-base stability; Kidney salt and water stability; middle and stream; Thermal stability and thermoregulation; nutrients and digestion; Hormonal regulate; imperative apprehensive process and senses
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Extra resources for Color Atlas of Physiology
Sample text
A large portion of chemical energy provided by foodstuffs is utilized for active transport once it has been made readily available in the form of ATP (Ǟ p. 41). The energy created by ATP hydrolysis is used to drive the transmembrane transport of numerous ions, metabolites, and waste products. According to the laws of thermodynamics, the energy expended in these reactions produces order in cells and organelles—a prerequisite for survival and normal function of cells and, therefore, for the whole organism (Ǟ p.
Characteristics of active transport: ! , it has a limited maximum capacity (Jmax). , a carrier molecule will transport only certain chemically similar substances which inhibit the transport of each other (competitive inhibition). , each has a different affinity (~1/KM) to the transport system. Active transport is inhibited when the energy supply to the cell is disrupted. All of these characteristics except the last apply to passive carriers, that is, to uniportermediated (facilitated) diffusion (Ǟ p.
383). Cytosis is a completely different type of active transport involving the formation of membrane-bound vesicles with a diameter of 50–400 nm. Vesicles are either pinched off from the plasma membrane (exocytosis) or incorporated into it by invagination (endocyto- sis) in conjunction with the expenditure of ATP. In cytosis, the uptake and release of macromolecules such as proteins, lipoproteins, polynucleotides, and polysaccharides into and out of a cell occurs by specific mechanisms similar to those involved in intracellular transport (Ǟ p.